VG Protagonist who endured the most punishment?

[Zeema]

Kratos easily.

Has to kill endless armies of monsters and undead. Killed his wife and kid, covered in their ashes forever.

He has literally been to hell and back.

3 times

but i would say John MArston

Gets Shot, Gang Abandons him, Family Gets Kidnapped , Gets Shot by a Mate and Evil Player's who run him off Hills and make him stand in front of trains

 

[j1m2s]

Doom Guy. That man can be taken down to 1% health, bleeding through every pore of his body but somehow, he recovers so long as he finds a box full of medical equipment.

Seconded

If that's considered, then Duke Nukem (3D, not Forever)

 

[BanicRhys]

That I've played? Probably Cole MacGrath, he gets burned to a crisp, mind raped several times, forced to kill his girlfriend, betrayed by his friend, his powers drained, has to electrocute himself several times (blast cores) and dies.