@Ven: After the events of WAOA1, Joe went back to his home world to find it under siege by the Pie Lord and his Baked Goods army. The Pie Lord was presumed to be an idea of the creator that was never given a home world and essentially existed as part of an idea. Something however changed that and allowed him to get to Joe's universe. In the start of WAOA2 on page 1 there was a moment when a stickman and woman came through a portal very similar to Joe's portals scouting new universes to take over. However once Joe returned to the 3D world in WAOA2 we never heard of any culture being attacked by him. Joe lost his ability to call upon the 'Joes', and started having spells where his powers didn't work as well, or he'd just plain be tired. In WAOA1 he only slept a few of time throughout the entire thing, the first being when they escaped from NYC and his jetpack exploded on him. At the end of WAOA2 Joe needed to get off the dying world and managed to use the dimensional transporter and his powers to rip a portal open so he could escape, and so came the 992 universes he traveled through looking for the others in WAOA3. Ten years passed.
When WAOA3 came, Joe had 'grown up', he looked different and had apparently changed his appearance a bit so people would be a little more accepting of him. Joe had many different fights and whatnot, but he also had signs of weakness.
As for the red mist stuff, it has now happened three different times. Twice in WAOA3, and once in WAOA2.