I was excited for Prey 2 after that amazing trailer, but after seeing a bit of gameplay I'm gonna hold off and wait to see what the full package has to offer.
Bioshock Infinite is up there, and I guess I'm curious for Mass Effect 3, purely because I want to see how the story ends for my character that I've had throughout the years.
I am curious for the new CoD game (hear me out), because unless they want to ultimately doom the series, they have to try something original. I'm thinking that we may see a future version of CoD this year.
Oh, and the Skyrim DLC. That counts dammit.
Edit: Wow, I forgot about a few here.
Hitman Blood Money looks pretty damn good.
Metro 2033; Last Light, looks interesting. I never played the first game, but I read the books and saw enough Playthroughs to know that this game has some potential.
Dishonoured looks original and interesting, so be on the look out for that.