What is the biological reason for why things die?

Recommended Videos

JoJo

and the Amazing Technicolour Dream Goat 🐐
Moderator
Legacy
Mar 31, 2010
7,170
143
68
Country
šŸ‡¬šŸ‡§
Gender
♂
Although I'm sure someone has already said this, organisms age because in the long run for the survival of genes it makes more sense to concentrate resources on reproduction rather than repair. Why waste all that energy on keeping a being alive when eventually it will either be killed by a predator or overcome by a deadly disease?
 

thiosk

New member
Sep 18, 2008
5,410
0
0
Kukakkau said:
The body's like a factory - you keep having to put substances into it to keep it going but eventually the machinery will decay and stop working
This is why I love the idea of cloning organs ex situ and then implanting them back into your body at various stages in life. Replace your heart, liver, and kidneys at 50, your lungs digestive system and various bony areas at 60, and from the age of 40 on, nearly continuous skin-graft from freshly cloned skin.

Once we figure out some neat new brain chemistry, we can live forever off cloned parts.
 

tweedpol

New member
Nov 19, 2009
76
0
0
2 major reasons.

DNA replication can only go in one direction and can only add on to an already existing chain. This means it requires RNA primers (short RNA lengths to stick new bits of DNA to). RNA primers are replaced by DNA later, except at the beginning of a chain where there is no preceding sequence to add the replacement DNA to. This means DNA shortens every time it's replicated. So after lots of cell divisions this starts eating away at the actual genes. Telomerase can increase the length of the protective end sequence but if it were active in all cells you'd end up with lots of cancers (uncontrolled cell divisions).

A MUCH MORE IMPORTANT REASON: genes promoting very long life (ie. no aging) can be selected for (if you breed say mice together who live a long time you will end up with a breed of very long lived mice). But in nature there is little selective/evolutionary pressure on animals to avoid aging for long times since the older an animal gets, the more chance there is that it will have been killed by disease/predators. This means a mouse in the wild who would live 8 years will not have any more offspring than one which would live 3 because the chances are that by the time they are both 2 they'll have been eaten by Hedwig. curse you, Hedwig.
 

Dags90

New member
Oct 27, 2009
4,683
0
0
The real answer is "We don't know, yet."

We have some things that correlate with cell aging, but there aren't any known causative agents.
 
Apr 29, 2010
4,148
0
0
well, for one thing, the cells in one's brain do not regenerate. Once they're gone, they're gone. Also, over time the body starts losing the ability to heal as efficiently as it used to. That's when we get system failure.
 

ajemas

New member
Nov 19, 2009
500
0
0
Entropy is natural for all things. A quick look at physics will show that everything eventually breaks down.
From a biological standpoint, we are programmed to eventually break down and die. If organisms aren't dying, the evolution cannot occur. Also, overpopulation would run rampant if there wasn't a natural decay in creatures.
It sucks, but everything has to die.
 

chaos order

New member
Jan 27, 2010
764
0
0
NoseDigger said:
Oxygen is actually poisonous.

I think it was said that it forms free radicals (highly reactive) and then these in turn damage our DNA. something like that.
bingo! u r correct, this mixed with the fact that errors occur when our cells replicate, mistakes can occur
 

Shock and Awe

Winter is Coming
Sep 6, 2008
4,647
0
0
DNA, I do not remember exactly though, if I remember correctly its a "flaw" in how it replicates in that it is slightly shorter each time.
 

supflidowg

New member
Feb 27, 2009
5
0
0
A true "natural death" is caused by small faults in cells that replicate in cellular division that get worse and worse the older you get until the cells replication ability slows so far that the major organs just slow and shutdown.
 

Tetranitrophenol

New member
Apr 4, 2010
233
0
0
Im not expert in the matter, but from what I have read;

You die because you breathe air. Oxigen itself is a very poisonous gas,( not to mention volatile). Once you take a breathe and process air, these annoying particles called Free Radicals are a remanent of the whole process. The thing is that they are very very small, enough to go through your cell's membrane but not enough to avoid crashing against the DNA on the cell. This process over the years begin to degrade cells in your body to the point that kills them, and your tissues (heart, liver, muscle) begin to degrade.

When we are very young, our body has a nifty defense against these particles called anti-oxidants, but once we reach a certain age 25+ our production of anti-oxidants begins to diminish, leaving us open to the Free Radical bombardment, thats why Doctors encourage the consumption of foods with high levels of anti-oxidants in them.

Trees, live for hundreds of years since they don't process oxygen, in fact they exhale it, slow animals, like the turtle, tend to live for considerable amounts of time even tho they breathe oxyngen like ourselves, the difference is that their heart beats once every few minutes and they dont need to process oxygen all that often. On the other hand Mice and other animals which their heart beat to the point that it sounds like a buzzard (bzzzzzz) tend to have very little life spans since they are always on the run. There have been people that have chosen a sedentary (with healthy diet)life style and have considerably reduced the effects of aging in their bodies.

in short, every time you hold your breath, you are giving yourselves a few seconds of extra life!
 

meece

New member
Apr 15, 2008
239
0
0
Plazmatic said:
close, except we actually are NOT programmed to die, we are only programmed to live, the reason we die is because our DNA is damaged over time, and the repair process in our bodies worse and worse (this explains ageing and the slowness of healing as you age) However rest assured, in your life time we could have something that allows us to live thousands of years, A certain scientist featured both in the Chicago museum of science and Industry, and on the Discovery network has already shown us he is working on it, has made a mouse that normally lives 2 years live five, and has made nematodes (small microscopic worms) live instead of maybe a day, to 6 months. With in 20 years we could have something that would work as a life elixir.
That's not entirely true - cells *are* programmed to die in a process called apoptosis. It's the reason why when you're born you don't have webbed feet+hands, the cells in the webbing "suicide" if you will. Also one of the reasons people get cancer to rarely - apoptosis has to be prevented AND the controls for cell division broken otherwise the cell will just suicide before it can become cancerous.

There are *many* issues with somatic modification (genetic change in a mutlicellular organism in a way which is not heriditory) I think it's fair to say that this is likely to go the same way as nuclear fusion "cool but impractical for now and long into the future". Or else be banned for the fears which it will induce. (THERE'S NOTHING WRONG WITH GM FOOD >_<)
 

Axzarious

New member
Feb 18, 2010
441
0
0
Ozzythecat said:
Because as thing grow and age the clones of your cells degrade with every batch, this is due to the fact transposons and centromeres occasionally "lose" a peptide or some phosphate groups are lost, so mainly as your cells essentially clone themselves the degradation carries down the line, until the degradation causes dangerous defects and mutations. There more to it but I don't know the exact specifics and I'm too lazy to type them anyway.
Well, thats part of it, but I belive there is a certian protien chain (Or chromosome, I cant remember) or whatnot that is reduced by half or a certian amount or something each cell divide. It is thought to be the main factor in regards to aging.

There are some organisms on earth immune to the effects of aging however. One is a species of jellyfish. It can still die from trauma or sickness though.
 

open trap

New member
Feb 26, 2009
1,653
0
0
We die because cell respawn is broken and god has yet to come out with patch 3.1.1
 

meece

New member
Apr 15, 2008
239
0
0
Tetranitrophenol said:
Trees, live for hundreds of years since they don't process oxygen, in fact they exhale it
That's actually not true - yes they fix CO2 to make glucose and release oxygen but they also use oxygen to release energy from that glucose in much the same way that all animals do. There's just more oxygen loss from photosynthesis than there is oxygen uptake in respiration.
 

ScRaT_the_destroyer

King of Fail
Nov 18, 2009
188
0
0
i believe that its due to random errors in the copying of cells in their mitosis(like seemingly most people here), though imho i'm glad of the finality of death, it gives us a reason to experience the world. I mean were we to live forever what reason would we have to progress science and to explore, other than for its own sake.

death gives us a purpose, ie by giving us a set lifespan of x years it is up to us to make the best use of that,
to learn, adapt and ultimately improve ourselves.


just my tuppence
 

Terezar

New member
Aug 16, 2008
19
0
0
Guttural Engagement said:
Hey Escapist, so I was wondering, what is the biological reason for why things die? I know there is a thing called photo-aging (Light causes things to degrade?), is that why? Like, after a while - maybe our bodies just can't keep up with the rate of cells dying because of photo-aging?
because if things didnt die the planet would be over run with organisms within three generations and everything would starve to death
 

Jake the Snake

New member
Mar 25, 2009
1,141
0
0
It's just the way things naturally progress. Everything has a beginning. Everything has an end.

....well except for the Universe. And Chuck Norris.