We'll hopefully see new games with innovative takes on fantasy and sci-fi settings, rather than ones that beat the same dead horse tropes over and over. We might see a sandalpunk fantasy game with a mixtec vibe, a sci fi game that includes genuinely 'alien' aliens rather than the humanoid people-but-with-slight-alterations variey, or fantasy games that take their influences from pre-tolkien fiction; folklore, fairy tales - a lot of it is creepy stuff.
Those off the top of my head. I've got better, but I'ma keeping them secret for now.