People who don't respect rules "just because they can", and that like to ruin other people's days for fun. I've met a few in real life, a few internet trolls etc. and it's one of the few things that really gets under my skin.
For lesser examples, I'll also agree with a fair few in this thread: the invincible plastic wrapping that seems determined to slice your wrists open should you dare to actually open it, Facebook/Twitter/whatever social site, alchool to an extent (I wouldn't mind it nearly as much if people used it responsibly), the Lord of the Rings (this I might get some flak for. It's not that it's a bad piece of writing really, from as much of an objective point as you can get with a book. Tolkien had a deep story and beautiful description...except he put that description everywhere it wasn't needed. His plot (at least if you haven't read the Simerilean [sp]) was basically: there were 20 rings. One was bad. Let's drop that one in evil-laval. The story really never drew me in properly and reading it was a chore overall. The very low-degree of magic is a more personal quip, but this IS the what annoys you thread), and those people who try to coat themselves in a "badass" persona and act with seriousness that they'd have no problem killing people and the like.