I'd love some totally batshit insane crazy unreal absolutely alien (not as "extra-terrestrial"!) settings - WHICH WOULD IMPLY TOTALLY BATSHIT INSANE CRAZY ABSOLUTELY ALIEN GAMEPLAY MECHANICS. That's what I percieve as the strongest/most important capability of games, to enable you to experience something that in our world is absolutely impossible, such as Portal(s), Braid, The Void... and that's sadly almost all the examples I know about (on that note, if you know about any game that fulfills the criteria I talk about in this post, let me know, thank you.)
More of games which you can't just pick up and play because "oh, it's just another shooter, I use WSAD to move, left and right mouse to shoot and wheel to change weapons". More games where you have to invest some time to understand the rules of the world, what you're supposed to do, which tools are at your disposal and how they behave. And NO, A SINGLE TWIST IN THE MECHANICS IS NOT ENOUGH (unless it completely changes the rules and the way the game plays).
Because this kind of exploration, discovery, leading to inspiration, and making me think about new ideas I haven't thought about before, is to me, the most important in any games. I'm fucking bored of basically any genre, just because of that - it's a genre, which means most of what I do in the game I've done a hundred times. I don't care if I shoot in 1940 or 2940, I don't care if I command units around from bird's eye view in 1400 or 3501, it's still the same, just different set-pieces. To me, it's as if all the movies had exactly the same plot, just in different country and time period.