The man who can kill aliens with a few kicks to the face, breath in outer space with no helmet, muster the physical strength to carry twin rapid fire rocket launchers, A FREAKING JETPACK, and the ability to drive women insane at the mere sight of him, not unlike Cthulhu, one of Duke's only true matches powerwise (Cthulhu would probably win, but it'd be a close fight)
OR
The man who can fight through a room full of demons using a chainsaw, defeat giant demons with rocket launcher arms with his fists (it's just hard), have the balls to volunteer to protect earth's citizens by holding off the demons as they escape to colonize a different planet while leaving him behind alone, kill John Romero, his creator, Blow up 90% of Hell 3 TIMES, and finally stay in hell forever so he becomes immortal so that if any demons attempt to escape again, he will literally shove a chainsaw up their ass and use the skull for breakfast. Not to mention having the weirdest fan fiction story ever and the most ridiculous comic of all time. He does all of this with the manliest armor ever, unless Duke's bullet absorbing tank top counts as armor, then there's debate.
Scorpion from Mortal Kombat gets a lot of credit, for constantly returning from hell to enter a fighting tournamet, where he proceeds to throw harpoons into people's chests, yell "GET OVER HERE!", pull them towards them, uppercut them into the air, then take off his mask to reveal a skull and breathe fire all over his enemy, to which they will burst into flames, scream, then explode, an unknown man squealing "TOASTY!" only moments afterward.
Or Dan Hibiki, of course.
Wait, what about this guy?
Only true men can carry large blocks of stone and allign them perfectly to build a giant fortress, as well as survive explosions from kamikaze shrubs.