Some chick from Lost Planet had me obsessed for about a week, now I don't even remember her name. I really wish I used those words without "Lost Planet" in the sentence, but I did. And, again, a weird obsession with Chun Li. I barely even played the Street Fighter games, but it's there. Cortana, because I believe if we do get the technology to make video games solid, do-able people, we could make cortana a solid do-able person. Harley Quinn and Poison Ivy from Arkham Asylum, for obvious reasons, and because one of my friends dressed as classic Harley for Halloween this year and I've been aroused by Quinn ever since. Yuffi, from Final Fantasy 7 (in case you didn't know, you bunch of geeks), another game I didn't play...
I fantasize about wrapping a crowbar in Alyx Vance's skull, but I don't think that counts as a fetish... for obvious reasons... And I'm not saying the real world shit I'm in to, again, for obvious reasons.
EDIT: Shiva! I forgot Shiva. Another game I haven't played, but I find her surprisingly sexy. Oh, and Zoey from L4D, but that might just be because me and my friends have a superstitious belief that whoever plays Zoey will win, and I've become attached.