Nah, I wouldn't.
Why? People don't have instincts. Not like animals. If I see animals running in the same direction, there's trouble about and they know it. They also have a better idea on where to run, thanks to greater senses. People? We're a bit limited. Our senses are average, mostly, and our instinct can be countered by personality and intellect. Perceived safety is an opinion generated in the mind, not necessarily confirmed by any other sense. Humans can just as easily run into danger as out.
So, if I see a mass of humans running off in a direction, I would rather employ a different talent: Stealth. Run when there is danger and the threat can find me. Be quiet and the threat will, in all likelyhood, follow the mass of loud people.
This would, of course, change immediately if it was not something you could outsmart, like if World War 3 breaks out and people are running from bombs. You run from bombs, definitely. I guess it really depends on what the problem is...