I've been in bands, I currently work in Television, and I've had people recognize me all the time, and I've even signed autographs. I would never, ever say "I just don't get fans", because whatever these peoples motivations are for loving you, they just do, and if you put yourself out there it's just something you have to deal with. A better response would have been "I appreciate people taking time out of their day to view my work, thank you all for supporting me!".
In a fan-centric business, be it wrestling or internet videos, it's very important to make sure the fans know you appreciate them, or else they ain't coming back, and you have less butts in seats. Not hatin on Yahtzee, just sayin', it's kind of a bumbling response when he could have taken that time to thank the people that got him where he is today.
Ride the wave and be happy for what you got, Mr. Croshaw, there's a lot of people who would kill to be in your position, and it most certainly won't last forever. But, as a fan of yours, I hope it does.