Poison, if done well in a game (so that it actually does something), or anything that does damage over a long period of time. There is nothing quite like standing back and watching a guard die while looking for you after hitting them only a few times with the poison. And there is also nothing quite like having an opponent keep trying to kill you, while you do absolutely nothing to defend yourself, only to have them die.
Also, when possible, I like to kill very tough baddies with underpowered weapons, preferably also dodging all their attacks as well. Though explosives are always fun. Maybe a combination of the two would be even better... ?
Other than that, when those aren't options (as in, most of the time) I like to mix things up as much as possible. Variety is the spice of life; right next to Poison and Explosives.
Also, when possible, I like to kill very tough baddies with underpowered weapons, preferably also dodging all their attacks as well. Though explosives are always fun. Maybe a combination of the two would be even better... ?
Other than that, when those aren't options (as in, most of the time) I like to mix things up as much as possible. Variety is the spice of life; right next to Poison and Explosives.