Here are a few of my choices:
Omega:
Omega, a station in the Mass Effect series, is a hub of lawlessness, and profit, if you've got the right connections.
Reach:
Where Spartans are born. Who WOULDN'T want to go there?
Onyx:
Forerunner Sheild World. It'd be fun to go looking for the lost S-IIIs.
The Ark:
As someone mentioned before, this is where the Halo array was created.
Vulcan:
Live Long and Prosper
Quo'Nos:
Admit it, you all think Klingons are awesome. (And in the new Star Trek MMO, they're in an alliance with the Orions. A very...alureing destination indeed.)
Terminus:
The home of the Foundation, in Isaac Asimov's Foundation series.
The Cocoon and Gran Pulse:
Might be fun. (CHOCOBOS!!!!)
The Moon:
Eh, why not?
Coroscaunt:
The city planet
The Death Star:
Wait- THAT'S NOT A MOON!
Aleran:
Oh, wait......
Tatooine:
A nice destination for those in favor with the Hutts.
Risa:
Any Star Trek fan will understand this choice.
I think that's about it...