Yahtzee sort of touched on one of the things I don't like about role-playing in ME2. If you actually play the game making all the decisions and saying all the things you would in real life (as you expect would be the point of games like this), you get punished at the end of the game by being somewhat gimped in conversations and your options to affect the story. It's almost as if the game is designed to be played either completely Paragon or completely Renegade, with little real incentive for people to play as themselves.
For example, it isn't, "Hmm, I'm going to spare this guy because he didn't do anything wrong"; it's, "Hmm, I'm going to kill this guy because I need more Renegade points to convince Miranda to get over that stupid argument she had with Jack."
It's supposedly "an option" to be neutral, but Paragon and Renegade are really the only big options there are (there is no colorful Neutral dialogue to choose from, for instance), so it again comes down to being either a hippy wonderboy or a racist prick with a sweltering ego.
By the way, anybody else think Commander Shepard immediately became creepy whenever he started hitting on people? The combination of the slight uncanny valley and the strange seductive lines made me feel a little ashamed to be playing him.
"Come on, Tali. You know you want this."