Hypothetical Real Life One-Liner:
Jackass: What are you, gay?
Me: No, I'm bi.
Fictional One-Liner:
Questioner: Are you gay?
Person: No, I'm German. (cookie for the first person to figure out what it's from. Hint: it's an Internet series, and is not Red vs Blue)
Real Life:
Nancy Astor: Sir, if you were my husband, I'd poison that drink!
Winston Churchill: Ma'am, if you were my wife, I would drink it.
or
Person: I would vote for Satan before I'd vote for you!
John Wilkes: Indeed. And if your friend declines to run, I trust I can count on your vote?