Best:
- Persona 3 & 4, damn these games have great voice acting. Also some top tier talent in here as well (Troy Baker as Kanji Tatsumi being the most obvious)
- Dragon Quest 8, it gets really impressive when you realize that each "region" of the game speaks with a different kind of British/Isles accent.
- Shadow Hearts: Covenant, this game is the hammiest of the hammy but damn does it fit the story and make you fall down laughing when appropriate.
- Mass Effect 1, 2 & 3, not much to say about these other than some top notch voice work and voice direction. Best of the best.
- Dragon Age 1 & 2, same as above really.
- Uncharted 1, 2 & 3, while Nathan Drake sounds like... well... a Nolan North character, Sully, Elena, Chloe Frazier, Flynn... all pretty damn fantastic.
- Arkham Asylum & Arkham City, because it's KEVIN CONROY and MARK HAMILL! The BEST Batman VA and the BEST Joker VA... on top of that you have Nolan North putting in an incredible performance as The Penguin in Arkham City.
- Bioshock Infinite, this game just wouldn't be what it is without the great performances of Troy Baker and Courtnee Draper.
Worst:
- Just Cause 2, though this almost gets into "So bad it's good" territory because the VA in JC2 is just...so...BAD.
- Resident Evil 2, the first time I ever noticed really corny VA in a Video Game... just... so many bad lines... though not as many glaring ones as RE1.
- Tales of Xillia, Teepo... seriously... shut the hell up... the voice director who cast you needs to be fired.
- Star Ocean: Last Hope, the worst of Anime Style Voices done by English VA's... but even the Japanese Cast is nearly impossible to take... so many characters with super annoying voices.