Brutal legend, hands down.
you've just arrived in 'ha ha, you're so gonna get fucked...by metal' land and you're going "oh fuck me, whatdoido?" as you're running away from cloaked skeleton demons who want to stab you until the sequel comes out, you're running through the temple of ormagoden, and the temple looks REALLLLLY COOL. while this is happening, you hear the opening of 'Children of the Grave' by Black Sabbath, which adds to epic build up soon to cometh.
then you ponder a strategy that would surely save your life and vanquish those do you harm 'til death; "holy shit, that axe looks awesome, i should totally pick it up" and then as you pick it up, lightning comes down from the sky and the kickass part of the song starts up. you then turn to your foes with axe in hand and with a violent cry, you shout "FUCK YOU" and rain down upon the demons with force of 50 grown men.
you see your guitar is in danger. as you rescue it from the hands of demons blood, you discover it can blow shit up with fucking LIGHTNING and FIRE. you equip yourself with pick in hand, play a quick lick only satan himself could play, and your demonic foes are then electrocuted through the power of HEAVY METAL!!!!
later you build the titans greatest invention, not a beast nor monster, a machine fueled by heavy metal, a druid plow....the duece...summoned before you through means of awesome guitar solos. as you start the hell beast knowing the opposition lay before you is far too many, the music ques with 'back at the funny farm' by motorhead and times perfectly with rest of the game ahead. you hit the nitro as first rythm guitar riff is belted out and you storm straight through your foes, no matter their strength, numbers, or size, they are defeated before you as the druid plow earns it's name. not only that, if you read the lyrics to the song, it makes sense with eddie's current situation; he has know idea where he is in such a strange and unusual land, but it's fast and loud and that's all he needs to make sense of.
that entire first level in brutal legend fucking blew my mind the first time i played it. completely blew my mind, melted my face, and raised all kinds of hell!!!!