I love Saiyuki, but always in Japanese. I love the characters, mostly - the male ones, not the female ones that are almost all cardboard cutouts that need to be saved. The male ones actually react with real emotion and, unlike some anime, stick to their beliefs even if something blows up in their face.
Plus, their personalities are almost palpably funny when you throw them together - a monk with a temper the size of Lake Erie and the gun to back it up, an ex-preschool teacher who gladly takes up an almostly motherly role and has the scariest rage!face you've ever seen, a womanizing half-demon with a heart of gold, and a 500-year-old demon who looks 18 and acts 10 who is constantly hungry. Tell me that does not make for good entertainment.