Sasha Kravinoff from the Gauntlet storyline in Amazing Spiderman. Why?
-Because of her actions, she meddled with the web of the future through Madame Web, only because she wanted to bring back her hubbie, Kraven the Hunter, who DID NOT WANT TO COME BACK IN THE FIRST PLACE, hence why he shot his face off with a shotgun.
-In the process of wearing Spiderman out she managed to:
Destroy Rhino's life and chance for happiness by making a new Rhino wanna-be kill the first one's wife.
Kill Billy Connors through The Lizard, resulting in a permanent transformation for Curt Connors after witnessing the death of his son.
Murder Madame Web in cold blood after she was of no use to her.
Sacrifice Mattie Franklin, the 3rd Spider-Woman as an experiment to bring Kraven back.
In the same way, end Kaine's life cause she thought he was Spiderman, thus corrupting the rebirth ceremony and rendering Kraven unable to die.
And then, having the balls to actually call Spiderman a coward and an animal while she herself considers the life of Kraven more important than the imbalance she will create and despite the fact that her husband is a certified psycho who 1)Ate Spiders 2)Buried a man alive 3)Figured the best way to live your life happily is to blow your head off.
Marvel WANTED me to hate this ***** and I really, really, really do. Selfishness and malevolence personified. I also hate her cause she got off easy. Kraven broke her neck. WHAT?! Nitro was forced to wear Penance's costume with all 612 spikes and got tossed in jail! And she just...dies? Why?!
You thought you could get pissed at the OMD storyline? This, this...pathetic excuse for a human being is not something you hate or even punch, it's something you tear its face right off.