Gasp. Not a single person here said Prototype? There's so much that wasn't concluded in the story. The gameplay was fun but incredibly unbalanced. Most of your moves were impractical and they gave you so many of them that you'd only rely on 3 or 4 attacks the entire game. The stealth aspect was also pretty half-hearted and lazy. It's pretty damned hard to be stealthy when all they do is put sensors and sentries all over the place. The soundtrack was pretty epic, though.
If they just made a sequel that fixed all of that...