In no particular order...
1. Deus Ex: Invisible War - This wasn't a terrible game or anything... it was just very average. While average isn't necessarily a bad thing, the fact that it had to live up to its predecessor's name killed it for me. If the game had just been called "Invisible War" I probably wouldn't have had a problem with it. But because it was a Deus Ex title, I couldn't help but notice all the things that it did worse than the original, and it really detracted a lot from the experience.
2. Left 4 Dead - This game just bored the hell out of me. I love zombie movies/games, and I tried really, really hard to get into this game... I just couldn't. It fell so ridiculously far short of all the hype that it had gotten upon release that I still regret the purchase. It just really didn't do much of anything right, in my opinion.
3. Gears of War - I straight-up don't understand what people like about this game. The characters are very undeveloped and fairly unlikable cliches, the story is more or less nonexistant, it frequently (and pretty blatantly) steals from much better science fiction works (which isn't really saying much, considering the first example that came to mind was the level where you had to stay in the light to avoid getting shredded by millions of little flying aliens - which is pretty much just the movie Pitch Black), the boss fights were cool looking but lacked very much in substance (anyone else find it kinda funny that the Hammer of Dawn always conveniently worked during boss encounters, but was absolutely worthless at all other times because a cloud or something was blocking its line of sight?), the game's visual theme was pretty uninteresting (up there with the original Quake with its multiple brown castles), and the combat was honestly pretty boring with all the chest high walls - it's hard to feel like a space badass while cowering behind cover. No real redeeming qualities here from me. Maybe the sequel fleshed things out a bit more, I dunno. Wasn't worth the time, effort, or money to me - even at bargain bin price.
4. Call of Duty: Black Ops - Disclaimer: I don't hate this game series, I actually like it quite a bit. I just don't like this one. The single player story did absolutely nothing for me, and the massive number of historical anachronisms were incredibly grating. As for the multiplayer... I just couldn't get into it. I thought the currency system for buying weapon accessories and decals was incredibly stupid. The weapons are very poorly balanced. The maps are honestly nothing special. And honestly, the game just feels very sluggish to me. I don't know if I'm the only one who feels this way, but compared to MW/MW2, I just feel like movement and aiming aren't as smooth - and I know for a fact it's not an issue of hardware here. And one last issue... the John Woo dive. It really kills immersion when 9 out of 10 people do nothing but John Woo dive, guns blazing, the moment they see each other.
5. Command & Conquer: Renegade - I was a HUGE fan of the C&C games back in the day. When I heard that they were going to make an FPS set in the universe, letting you see things from ground-level, you have no idea how ridiculously, and somewhat embarassingly, excited I was. With each release date delay I just got more and more excited, because I thought it meant that they were taking their time with it to make the best game possible. Then it finally came out, and failed so miserably to live up to my expectations. The graphics weren't particularly good, even for their time. Vehicle control, while uncommon at the time and fairly cool, was still pretty clunky. The characters were pretty unlikable (especially Nick Parker, the player character). The story was pretty bad, even by cheesy shooter standards. The AI was hilariously bad (especially the soldier in your squad with the rocket launcher, who would frequently try to fire at enemies despite there being an obstruction blocking line of sight, resulting in him blowing himself up). And while the multiplayer was pretty cool, the horrible lag made it unplayable at times.
6. Brink - This game is a thorn in my side. It was praised for its customization, which turned out to be pretty bland. A handful of firearms that all perform pretty similar, a handful of accessories which don't really do much, and maybe ten or so different costume pieces for each 'slot' on your character (which you can't even pick custom colors for, you have to choose from a few preset color schemes) - and to top it off, you had to unlock everything since it wasn't available from the start. Then there's the laughably bad singleplayer, which is actually also the exact same thing as the multiplayer, which gets incredibly old. Lots of talents that are either worthless or incredibly situational to the point where they're fairly worthless most of the time. This game just did nothing for me, and completely failed to deliver on the hype surrounding it before release.