Well, there were a lot of games back in the NES/SNES days which I played through in one sitting, but that was how it was back then. The only two recent games I can think of are Portal and the Scott Pilgrim game, which are pretty short as well, so no big deal. Even if I had the time, I wouldn't want to play "marathon"-style, losing sleep and whatnot.. though occasionally I will go for, like, 8 hours straight when I can, and feel kinda gross afterward.