Fallout 3 was by far the biggest let down up until Broken Steel was added. Now I can actually do shit after I've saved the world!
Also, Too Human was pretty annoying. I know, I know, it was a bad game in general, but the storyline actually seemed alright, so I played all the way through to see what would happen in the end. Once I got there, I realized that I really should never have even considered getting that game in the first place. I probably don't need to worry about spoiling anything because I'm the only person dumb enough to actually play this game all the way through, but I won't go into any details. Suffice it to say that there's no god damned closure, and I'm not buying the sequel to get some!