Killer7 is unlike any game I've ever played.
Also maybe check out From Dust, it's a very beautiful and creative god game with a pretty cool and subtle story.
My honest suggestion, which is what I do when my life is being a bastard and I'm worn out on every other genre: Play Civilization. Civ V is a great deal of fun, and nothing helps you forget about your shitty world quite like forging a brave new one that doesn't suck.
Plus by the end I feel like I should run for president, last time I was the leader in science, diplomacy (2 votes from king of the world or whatever, and one of those was basically Nazi Germany being upset because I wouldn't help them crush the innocent), money, and culture, with the fewest number of cities (I think I only had 4 or maybe 5. Beautiful coastal trading towns with acres of untouched farmlands to feed their massive populations) and never once going to war (except to defend my beautiful lands, it turns out that it's absurdly easy and cheap to create and maintain a really powerful defensive military, so long as you keep it defensive. Who would have guessed constantly looking for war wasn't a sound political agenda?).
I would kill to live in a world where that's the sort of country we're shooting for...