I'm not sure it's real, but more to the point I can't really find myself caring about Duke Nukem anymore. Yahtzee was actually right when he talked about how our culture has moved passed the immature, hypermacho antics of Duke Nukem. The game looks like Half-Life 2, except the Duke, unlike Dr. Freeman, just won't shut up with the stupid, psuedo-macho one-liners. It was kinda cool when I was 10, but it's just immature and outdated now.
The way I see it, there are two paths that any new incarnation of Duke Nukem could go:
a) He could go the path of modern shooters and adopt a grim, psuedo-neanderthal macho attitude similar to the path taken by Bionic Commando (this will likely end in failure).
or
b) He could go the path of humorous, over-the-top throw-back parody, notching the cheese up to 11 and poking fun at the franchises history, similar to what House of the Dead: Overkill and Matt Hazard of Eat Lead! (which is itself a parody of the Duke Nukem franchise and it's cliches, satiracle macho-ism, and Hasselhoff/Shatner cheese factor).
I believe the 2nd path could actually prove to be successful. Duke Nukem was designed originally as a parody of over-the-top 80s action heroes, despite the straight-faced macho appeal he garnered during the 90s. Any hope the Duke has of a comeback requires him to not only re-embrace the level of parody existent in past incarnations, but rachet it up to a whole new crazy level, as the humor and satire hasn't aged well and if underdone will only come off as another generic, wanna-be tough-ass protagonist that come dime a dozen in modern shooters.