While the series certainly wasn't great, i'd really like to have a Game with the Basic Premise of "Sliders".
For those who don't know what i mean: Due to some freak experiment accident you and some strangers and friends are thrown into an alternate universe. Same time, same place, but always different rules and civilisational stages, like one universe in wich earth is conquered by the Sovjets, another one where a virus has killed most of civilisation, another where earth is still like the middle ages, another one where humans and aliens live together on the planet etc. etc. And of course, you try to go back to the "original" one
It should be a linear, but still open world game, as you have always a time limit before the portal to the next universe closes off, and to make things interesting, you shouldn't be able to travel between universes with the help of a portable device, but a stationary machine you have to reach (wich, of course, won't be easy most of the time).
And since the concept demands it, the Gameplay and Style should change in every new universe, so that the game sometimes plays like a shooter, sometimes like a stealth game, and sometimes just like a classic point and click adventure.
I guess it would be nightmarish in terms of marketing and financial success, but for me, certainly worth a try ^^