Okay. Lemme break it down. First up?
Sephiroth IF I had some form of control over him that he wouldn't or couldn't break. Who needs guns when you have a six-foot long sword and godmode turned on?
Kratos IF he wouldn't go ballistic and kill everyone on my team (including me!). He has chain swords, a vicious streak a mile wide, and makes for great entertainment when you set him loose.
And, of course....a female character to round it all off....Orihime Inoue. Technically she's in video games, and she essentially can reject reality. Zombie bite? Only until she busts out the healing. Car wrecked? Not for long! Gun out of bullets? Hah, you wish.
Negating those former two ifs, my backups would be...
Kelly-087. She's not bad looking if you need to jumpstart the human race, and she's -stupidly- fast. Bait and superspeed arse beatings, coming right up!
Aaaand...I'd have to say....Dante from DMC. He's got style, an arsenal of demonic weapons, and occasionally, very large guns.