I got it on the PS3 and I got some problems indeed:
- Primm's deputy being stuck with his head in the ceiling. Glad I could still talk to him though.
- Various pathfinding issues with Boone, some resulting in him keeling over all of a sudden.
- One of those graphical glitches where a texture stretches out and fills half the screen with an odd smear, in this case it was the knife of a raider.
- The screen, or parts of it, suddenly flickers. At least I hope it's the game, and not my TV. Never had it with any other game though.
- Lots and lots of stuttering.
- One or two complete crashes.
It's nothing gamebreaking, but can get annoying. Thanks to the game saving so very often I've never lots a lot of progress, and I'm still enjoying the game a lot.