Yeah I do. Had quite a few female friends when I played WoW and Guild Wars (I don't actually converse with people in other online games like shooters etc.), always got along great with them and we played together all the time - in fact, I usually ended up in a close friends group with most girls we had around and chatted with them loads during downtime and such.
Can tell you they didn't get bothered much either, there was the occasional comment I suppose, but it was a once in a blue moon thing and most of the time, people really welcomed them with open arms (and not in a creepy sort of way). There was only one incident where I saw a girl actually bothered by someone (the other rare comments were simply ignored). That said, I suppose MMOs have a larger proportion of female gamers, so I'm guessing stuff like shooters and the like are worse experiences for girls (though note, I have no numbers or experience to confirm that, just a guess from the experiences I read around Escapist and the like).