No.
I loved the game. I'm a sucker for coop games, and it has really fun gameplay that I have a blast going through with friends. We've played through the game several times and through all of the content.
But the game fails to make any of us laugh with what was obviously meant to make us laugh and comes off as annoying, and just makes my eyes roll. We're not high strung people, we don't laugh with the game, but rather at it. Most of the genuine humor we have in BL comes from the inadvertent videogame stupidity. Like the time that my friend playing as Brick accidentally punched Clint Eastwood right off his crane and killed him. That was hilarious. Or when we fought the Destroyer and he turned out to be a total pussy. That was also hilarious.
Other stuff which was meant to be humorous strike me as complete misses. Such as the Claptraps, those things are awful. No thanks. The boss "taglines" as neither funny, or quirky. When we ran into Knoxx, and his tagline was "Doesn't like mondays! ^_^!!!"
Me and my friends in unison: "LOL WHO DOES LIKE MONDAYS!?!? A HURRR HURRR HURRRRRRRRRR."
The game was good regardless of it's failure to please me with any of it's unbearable writing. And I would like to see some kind of a sequel for it, although I won't hold my breath for any humor.