Depends on the audience.
Humour can never go too far, however it can be insensitive and rude to use certain types of humour around certain people. Saying this to my English teacher has a 50/50 chance of getting a laugh out of him - cause he finds this sort of stuff funny, and enjoys games and internet pictures a lot - or on having gone too far - as he is Jewish and a number of his family members were exterminated by the Nazis during WWII, though this doesn't stop him making Nazi and Jew jokes.
However, bring this out at a party where everyone loves pokemon, and is capable of understanding it means no offence to anyone, and its far more likely to get a good reaction, and not cross any lines.
Its like something that happened a year or so back during the temporary return of "Hey Hey its Saturday", and Australian TV show. A group came on acting as the Jackson 5. Not being black, they had black face paint on, except the guy playing Michael Jackson who had white facepaint on, and they did a song and dance. Pretty much everyone loved it, and found it funny or entertaining. There was some American guest judge or whatever who for some reason took deep offence to the face paint issue, and there ended up being apologies and everything because whilst the humour wasn't bad, and most people had no problem with it, with that one person added to the mix it became the wrong audience, and probably inappropriate to show.