Xeno311 said:
Yep. My best friend is a girl, I completely trust her, I don't have any feelings towards her, and she's in a relationship. Ergo, yes.
For now. Besides, you can only know your side of things. You don't know that she's NEVER had feelings for you, do you?
Basically what I'm saying to everyone who says "yes" is that it's pretty much statistically impossible for a (fairly attractive) straight man and (fairly attractive) straight woman to be very, very close friends, spend a lot of time together in close proximity and never entertain thoughts of being intimate with or entering into a romantic relationship with the other.
Now family, that is what I'd consider the ONE exception.