An enemy is an enemy. They stand between you and a goal and they must be dealt with. In this case, they have a gun; you have a gun. It is simple. Whether the enemy is a man, a woman, an alien, or whatever else you can think of, they are trying to kill you and you are trying to survive. I don't have any problem whether a man is shooting at me or a woman is shooting at me, I just care that both genders are represented equally.
If it is an urban street gang game (Saints Row or GTA) then I would be baffled by having a lot of female enemies. I watch the show Gangland all the time and the female population of gangs are either prostitutes, drug dealers or just the girlfriend of gang member. A rough percentage of woman that are literal gangsters is somewhere between like 1% and 2%. In Mass Effect or even just a modern war game I would expect to see a decent population of female enemies and ally soldiers considering there are a good bit of females serving in the military.
If it is an urban street gang game (Saints Row or GTA) then I would be baffled by having a lot of female enemies. I watch the show Gangland all the time and the female population of gangs are either prostitutes, drug dealers or just the girlfriend of gang member. A rough percentage of woman that are literal gangsters is somewhere between like 1% and 2%. In Mass Effect or even just a modern war game I would expect to see a decent population of female enemies and ally soldiers considering there are a good bit of females serving in the military.