Renegade, usually, as it seems much more fitting of a spectre bent on murdering ships of epic doom and apocalyptic epochs. Paragon runs always feel more satisfying for me, though.
I have yet to play ME2 but seeing as they are all pretty renegadish, themselves, the answer seems plain.
I have yet to play ME2 but seeing as they are all pretty renegadish, themselves, the answer seems plain.