Not on my first try, but Imperishable Night. On Normal.
You know, this sort of thing.
Maddening, I tell you.
Note: This includes the ridiculous "last spells" at the end. You know, where she fires off a bullet pattern, vanishes once you beat it or die, then repeats the process after reappearing. If I was just trying to finish the game with no deaths (just to clarify, I did beat the game with no deaths, not just stage 6, though I DID use bombs, no slow mode before you ask) it would have been a good deal easier.
Edit: I suppose every roguelike counts too. I've beaten Nethack, ADOM and Dungeon Crawl Stone Soup. You know, eventually. I died plenty of times, but since you can't save and you start over whenever you die, it probably sorta-kinda-half-counts.