Protagonist is Coming ACT LIKE A NPC QUICK

[Steamtech]

"Chicken Chaser!"
-the reason why it is absolutely essential you get a new title as quickly as possible in the original Fable

 

[assassinslover]

*stares unwaveringly at a very interesting brick wall/have conversation with self*

oblivion/Fallout/etc

 

[Caiti Voltaire]

"Welcome to Corneria"

(Okay, not in a game per se, its an 8-Bit Theatre reference )

 

[LunaSocks]

"Yaaay!" "Thank you!" "You're our savior!" Fable NPC's after you've beaten a quest, moments before you slaughter all of them.

 

[thatguy1]

(character is 5 spaces away)
"EEK! Did you touch me?"

-Pokemon

 

[zombays]

Half-life 2
"Reload, Dr. Freeman!"
*proceed to continually go in and out of door like OCD freak*

 

[nackertash]

Heya! It's me! Imoen.

 

[Belthalmel]

HEY! LISTEN!

 

[MeTheMe]

"He must be late! And she must be beautiful!"
Assassin's Creed 2

 

[bak00777]

"Press B to jump!"

-Unforgotten Realms

 

[TheRundownRabbit]

Uhh Uhh (lets do this Bethesda style)
"Hi there, Im here to help you but I'll end up being totally worthless and my character has no plot development at all....batteries not included."

 

[LightOfDarkness]

GRAAAAAAR *chops off your head with an axe*
-The Headless Horseless Horsemann from TF2

 

[Someperson307]

I'd secretly kill every human in this temple starting with 2 random soldiers and then ending with the human who saved me.
-Yurt, The Silent Chief

That's why you kill that bastard and take his sweet armor.

 

[biGBum333]

''ooOOO AA AAA''

monkey from system shock 2

 

[Archemetis]

'Talking to people multiple times can reveal lots about their character...'

...

'Talking to people multiple times can reveal lots about their character...'

-Graham Stark.

 

[Blubberburg]

"Holy shit this car has a CD player?"
Random person in a car in Saints Row 2, normally just before i shoot them in the face and steal their car

 

[Marsell]

"Over here, stranger."
"Got Somethin' that might interest you."
Best. NPC. EVER.

 

[CaptainKoala]

Hitman: Blood Money
*Magically know that the man approaching you in the exact same outfit as you is actually a highly trained clone assassin.*
'ITS HIM!'

 

[wrightguy0]

have something interrupt my pathfinding, then randomly spaz out into traffic to get hit by an oncoming taxi

GTA IV

 

[FalloutJack]

"Howdy, friend!"

*Watches as the player has a heart attack*

(Victor, from Fallout: New Vegas.)