Not sure about comics, but I know of one manga that's pretty obscure, but I love it. It's called Franken Furan (Fran).
Warning though, only read it if you can handle gore and EXTREMELY dark humor.
The basic premise is this: Fran is a sort of super-amazing teenage surgeon girl. So amazing, in fact, that her operations are nothing short of miracles... or slaps in the face of God. Depends on your perspective.
Each story usually begins with Fran being presented with some sort of opportunity to use her amazing talents. But... things never go quite right. Oh, the operations are successful... but the patients usually get MORE than they bargained for.
For example, in one story, she finds a girl who's just been gravely injured. She saves her life, but... well...
WARNING, SPOILED FOR "OH MY GOD"
So, yeah, if you looked at that, you've got a pretty good idea what this manga's about. Highly recommended, if you're into this sort of thing.