thats not the best way to deal with that quest.Dexiro said:I actually found it better not to start fresh, i didn't manage to enjoy the game until i grabbed a ton of hints from other people.DaggerOfCompassion said:My game, I shall play it as I wish to.Bobic said:Play the game fresh without letting a forum full of people spoil the goings on of the game.
First off i'd advise getting your explosives skill to 30 during the tutorial.
Then when you reach Megaton at the beginning of the game talk to the Sheriff dude and say you'll disarm the bomb in the middle of the town. Then use your explosives skill of 30 to disarm it!
From that you get a free house! The whole quest takes like 2 seconds you just need that explosives skill to do it.
From then on you can hoard as many items as you want in your house and then filter out the stuff you can sell later on.
If you find yourself low on health often i'd recommend putting points into your Medicine skill. This makes Stimpaks more effective, which are your main health item.
Whether or not you follow the spoiler'd tips i just gave it's always best to just explore rather than follow the main quest. Hunt for some sidequests and do some random exploring and you'll find all sorts of crazy weapons and earn tons more money!
talk to the sheriff to start the quest, go and talk to mr.burke in the saloon he will give you a device to rig the bomb. after you speak to burke go back and tell the sheriff that burke wants you to blow up the bomb then go with him to confront burke. after the sheriff dies kill burke and loot both their gear. then when you get 30 explosives you can come back and disarm the bomb the sheriffs kid gives you the XP and money 
my advice is up your repair skill to as high as you can as early as you can will save you lots of money, then up lock pick , small guns and science. those 4 are your most important skills after them sneak medicine and speech are great.