The gaikai ads of roughly a year back were probably the worst ever. They loaded an empty java applet, forcing your browser to stop and load the java plugin whenever one appeared. I changed my settings on Opera to only run plugins on demand because of that. Other browsers couldn't do that though, so later I just uninstalled java entirely.
I also decided never, ever to do business with gaikai.
If you have Ghostery, it can remove the Taboola junk without removing ads. All you gotta do is...uncheck "advertising" in Ghostery's options, since Taboola is under the Widget category. It also gets rid of Facebook comment sections.
Alternatively, the taboola junk is sourced from cdn.taboolasyndication.com. Do with that what you will.
On the other hand, at least the Taboola crap isn't animated. At least not that I've seen.