I remember J. Michael Straczynski saying that he was doing The Real Ghostbusters as a reaction to his experiences for writing He-Man. A lot of 80's shows at the time (He-Man, She-Ra, G.I. Joe, Transformers, M.A.S.K., Thundercats, Silverhawks and Voltron) were repetitive and formulaic. Nothing ever changed, no one's character ever developed, nobody ever died, every episode centered around the villain's latest hare-brained scheme and the overriding goal of all of them were to be 30 minute-long toy commercials.
JMS knew that kids were smarter than that, and to his credit he really fought to give TRGB a level of quality that hadn't been seen before, and it showed. Many of the scripts were smart and clever as well as funny. I'd say both this and Robotech (and maybe even Centurions) were the best shows to watch at that time.
And of course, another legacy of TRGB was that JMS used his experience there as a showrunner on Captain Power & The Soldiers of the Future, and that ultimately paved the way for Babylon 5!