There were a lot of games a really disliked, like Super Mario Bros. (never beat it) or Street Fighter 2 (single player cheap opponent AI).
But the first game I truly HATED was Battletoads. If you weren't busy accidentally killing your teammate (or griefing each other), then you were getting bent over on the speederbike level. And, IF you somehow managed to get past that, the next level would probably kill you anyhow. And with no difficulty settings, the only thing to do was toss the thing and beat up the next person you see to vent your frustration, which ironically is pretty much like two player mode in Battletoads anyhow.
Yes, that cart deserved the same fate as ET for the Atari - gathered up, dumped into a big hole in the middle of no where, and forgotten. Except that I just brought them up. Damn it!