I decided to finally do a renegade run across the Mass Effect trilogy after playing pure paragon ages ago (and the 'good' track in pretty much every other game I've played). I was relatively fine during 1 and 2. There were a few things where I had to delay a second of two before being able to select the renegade option but all in all I could live with my choices. And I always had Mordin on my team during 2.
But then the genophage mission came along and since I was going renegade I resolved to take up the dalatrass' offer and stop Mordin from distributing the cure but since I'd let Wrex live in the first game (my Shepard was ruthless, not stupid) the only way to do that was to kill him. But I still spent every response trying to convince him to leave and when it came to shoot him I left it until the very last moment to pull the trigger. But then it showed me the scene afterwards where Mordin is bleeding everywhere as he goes up the tower and then tries to drag himself towards the console with his dying moments and fails at the last moment, dying, thinking he left the world worse than it was when he came in, because he was betrayed by a close friend. And that made me feel like a terrible, terrible person. But I tried to stick with it awhile longer but then discovered a few minutes later that Jack and all her students had died as I was too slow to go help them and that was it, I couldn't take it. So I reloaded my last save (3 hours in the past), completed Jack's mission and replayed the last four missions I'd done, getting the QTE to shoot Mordin again, but letting it pass.
I thought I'd be able to do a renegade run. I'm kinda glad I couldn't.
