Playing Pandora's Tower. Like, the whole thing.
You have to bring back beast flesh to the protagonist's girlfriend every so often or she turns into a monster.
If you stay out too long, when you come back she's half mutated, and on the floor, slime everywhere and all she says is "Careful you don't slip"
._. Makes you feel like an asshole for waiting so long
Clearing the game's bosses gives you master flesh to give her which is supposed to cure her, but about half way through... Well... I don't want to spoil it, but the cut scenes make it pretty evident that this probably isn't working as desired.
If you wait too long you feel like an asshole, if you actually progress you feel like an asshole.
I felt like just keeping Aeron (the protagonist) inside their base, where time apparently holds still just to spare the girl some misery.
(It's not all bad though, you can buy her gifts like dresses and jewelry and that cheers her up a bit)