I'd argue the Forgotten Realms interpretation of is the best (or if nothing else, the most logical one). Many adaptations of Vampires sadly try to take the "formula" (if you will) in a direction that simple doesn't make any sense.
The adaptations where the Vampires all have a secret society (or at the very least some secret rules they follow) that humans know nothing about, and they don't want the humans to know about just doesn't make any sense. Vampires: TM: Bloodlines, Blade movies, Twilight, Moonlight (TV Series), True Blood (where the vampires HAD a secret society, but came forward when someone invented some artificial blood the vampires could drink).
The problem with those is that practically, that's simply impossible. Vampires are predators by nature, with instinct often overpowering logic, and you simply can't prevent that at least not SOME of them will end up exposing them at some point. It simply isn't going to happen. Humans (as in, all humans, or at least close) is simply going to find out sooner or later when bodies appear in the streets clawed up, and someone witnesses it and videotapes it. There is no "hideouts" that are secret enough in the sense that humans won't bump into them at some point. In the modern information age, it's especially impossible to keep a society like that hidden. It simply isn't going to happen.
The most logical Vampire adaptation is therefore the ones where Vampires are simply Undead and people know about them, just like they know about other undead creatures like Skeletons, Zombies etc. People try to avoid them, but they KNOW they exist, and some heroes (Paladins in particular, but also priests) exists to fight them. I'm not saying the other adaptations don't have their place, but this one is definitely the one that makes the most sense.
Btw, the original Vampire adaptations (as in, Count Dracula etc.) are also great, but only if the fiction is kept a few centuries back. These adaptations simply wouldn't be able to survive in the modern world, because they rely on mystique to keep things interesting, and there are very few non-fiction things in existence in the information age that has any mystique left to it. I'd love to see the reaction on Count Draculas face when local law enforcement arrive with some government officials, the media and a search warrant, demanding that he pays his taxes.