Nut that I am, first vote goes to the Nosferatu for being well before the rest in movies at least...
But my favorite "vampires" are Touhou's own Remilia and Flandre Scarlet. immensly powerful, blood drinking, sunlight and running water weak, so they are classical in a lot of ways... not to mention each push 450+ years easily, if the data i have is to be believed.
Except that fan interps of Flandre end up pitching her as exceptionally crazy, and I liken her to a kid who doesn't know what she is doing- a super powerful being in a kids body who wouldn't know what her food really is, so given a normal human being, she'd spill the blood and not get any, but that's also because she stays in the Scarlet mansion and is fed cakes made with blood instead of going at necks.
oh, right, and because its Touhou they can rain more overt destruction then most vampires ever could if they turned their attacks on the populace.
Go, Remilia!