Tintin is pretty damn good, plus Captain Haddock, Calculus, and the Tompson/Thompson are some of the funniest characters in popular culture.
But I'm going to have to go with Asterix & Obelix, because, well, when you get right down to it, it's pretty much pratfalls, slapstick, and weirdly twisty serial-style plots. A&O, on the other hand, has some splendid wordplay and historical/cultural gags that just tickle me. Also, it's got some great artwork going for it, while Tintin's never quite appealed to me as strongly.
Nevertheless, they're both great, and I plan to see the Tintin movie when it comes out.