Quite a few. A sampling:
-I long to see a return of mission-based spaceflight games. A new Elite, eh? Okay, so I'll plan a mercantile trip, carry it out and make a profit, then run into a pirate and blow them away. Takes twenty minutes, and that's really all the game has to offer. No thanks; I've been a truck driver. But toss me in a Broadsword and tell me to take our four Jalkehis in a minefield with no wingman? Send me in to cripple the main guns of a superjuggernaut before it jumps in and blows our flagship away? Force me to impress Imperial cadets by clearing a minefield in an unshielded craft? Hell yes!
-A worthy successor to Master of Orion 2. The high throne of grand space strategy lies empty. Sniveling pretenders like Galactic Civilizations and Endless Space, unworthy of licking the king's boots, are hailed as worthy contenders for it, but they know in their hearts that the Quicksilver madness that drove him from the palace in 2003 mightn't last forever.
-On the note of strategy, and one I wish I could say I was surprised to not see mentioned above: Emperor of the Fading Suns. The game wasn't properly finished, let alone polished, and was advertised poorly, sold lousily, and was quickly forgotten about. But its ambition and attempted breadth of scale was something I'd never seen before, and wouldn't see again until a heavily expansion-packed Crusader Kings 2. Picture Dune by way of Battletech having a baby with Betrayal at Krondor by way of Civilization.