It is interesting how many people here (i assume men lol) want Fembots so badly. Say's a lot when you come to think about it..
By the Mid-21st century i would hope to see-
1)Huge advancements in the field of genetics.
Limbs and organs and blood cells can be grown specially for the patient from their own stem cells.
2)The effects of ageing on the human body are reduced so we have longer life spans. This may permit us to live even longer so we can see the possible reversal of the aging process.
3)Genetic Body Modification would be awesome, if possible. I would imagine features such as tails, cat ears, vampire fangs, and super-strong limbs would be popular.
4)Genetic revolution leads to GM crops finally being used to solve the famine problems in Africa and parts of Asia.
5)A more politically united world. Think of the EU today, and apply that model to the rest of the world. One common human government, one common currency, one military force. I doubt this would happen in our life time, but perhaps the foundations of such a thing could be constructed this century- it could mean war on Earth becomes a rarity, and everyone becomes more wealthy.
6)A growing space tourism industry, space stations become common, and colonies on the Moon. If genetic technology permits us to live into the 22nd century, perhaps we could live to see the foundation of Martian colonies, and a growing asteroid mining industry which would lead to deep-space exploration and colonisations. Once we have achieved that, then the long term survival of human kind is guaranteed.
7)Robots become common- it would make life a heck of a lot easier
8)As someone said before, total immerse reality's. (Like the Matrix) Perhaps if this technology is combined with the ability to download the human consciousness into a computor program, you could kill off your old human body and live in the computor simulation of your choice. You could make your own heaven.
9)Nuclear Fusion- solve the current energy problems and global warming.
10) A Data Base that contains "Everything". All the information that is stored across "teh interwebz" is constantly downloaded from all the worlds various servers and into a ginormous super computor which is kept in safe keeping in a military bunker deep underground. Safe from nuclear, nano, bio and chemical warfare it would be an archive of the summated human knoledge that we have acquired over the many thousands of years. That way, if human civilisation collapses completely and we find ourselves back in the dark ages- all is not lost, we have the archive.