It's either The Simpsons or South Park (earlier seasons). Those two have made the biggest impact in my life and are still some of the funniest shows ever. They both have so many great jokes you can use for a quick laugh.
Also loved The Chasers War On Everything, M.A.S.H, Futurama, Family Guy, King of the Hill, Full Metal Alchemist, Naruto (till about 133), Hunter X Hunter original, Bezerk, The Looney Tunes, Tiny Tunes, X-Files, Venture Brothers (early seasons), The Cosby Show, and some others I can't remember right now.
Sadly, most shows I see now are pretty crappy. MLP is the last one I was enjoying, season 2 is pretty crappy with the writing so I think it's already ended for me. I still need to get around to watching Breaking Bad though.