If you'll permit me to repeat what's likely already been said:
We all know they're hooting on about no more elevators, and that textures are no longer meant to jump out and scare you when they suddenly appear. However...
Big empty boring planetary exploration MUST DIE! I've completed the game10 frigging times, and the one thing I've come to dread the most in every single play through has been trying to pilot that awkward tumbling MAKO along barren cliffs only to be treated to more barren cliffs.
Mako's gone too, thanks to BioWare for that.
Deeper character interactions. Really, why should I give a rat's ass about Liara's mommy issues? Kaiden has problems with his past, but it's hard to care when that's all he's talking about. Everyone just felt two-dimensional, and I grew tired of them, fast.
More population! The Citadel, the very heart of the galaxy, where all known sentient life converges, and it felt about as large as an average shopping mall, and was sparsely populated. Hell, why only the Citadel? I wanted to know what Earth looked like at that time, or some other colonized planet that didn't consist of a lot of places I could not enter, or a pub and a police office. Such a big galaxy, but not exactly teeming with life.
Simon says X-Y-Y-A-B-Y-A-X-X-Y-A-A-B-X-Y-A-Y-X-A-B-A-Y-X-X-X-X-Y-B-Y-A *unlocking sound*
[you've just gotten a handful of upgrades that are weaker than anything you already have]
Bigger diversity in plot! if I'm evil, let me do really nasty things to hurt others! Busting a pushy woman in the chops is one thing, but how's about giving me the option to perforate her with my pistol? Worst yet, Hackett approves either way? C'mon!
More quarians, please! Tali was interesting, but what I was more intrigued with were the images I'd built up mentally of what the flotilla must have been like.
Romance is good, but what about making something more of it? It's a game where I've killed people, some of the killings were flat out murders, should I not expect equally candid positive emotional bonding? Do I really need to work so hard at sucking up to someone just to see their nude legs for 3 seconds?
Customizable appearances in my armor. I love BioWare.
Grenades. I had a habit of hoarding them because I never knew when I would see more again. Silly, considering that I was able to do so much more damage with a well placed warp and Wrex.
This one's kinda reaching, but my personal quarters were only useful for a couple of very minute things. What if that were customizable somehow too? Or better yet, what if they reflected my choices, sort of like the dorm room in Bully.
I could keep going, but these were some of the ones that bugged me most. The big empty space that was... well, space, is still the worst one. I'd almost swear the population of the Galaxy was less than that of Albion. There's so much wrong with this...